2/14/2023 0 Comments Autolab gpes software![]() The EIS testing was performed under high stability mode, where each experimental data point was taken as an average of 10 acquired points and presented as typical. It was shown that ethoxidol, in the concentration range of 90–600 μM, stimulates the electrochemical reduction of P450 cytochromes, with the maximum stimulating effects for CYP3A4, CYP2C9 and CYP2D6 being estimated as 181 ± 15%, 240 ± 7% and 110 ± 4% (at 540 μM ethoxidol), respectively. The EIS data were recorded using AUTOLAB electrochemical workstation (PGSTAT 302N, Metrohm, Netherland) in galvanostatic mode, controlled by a computer with Nova 2.1.2 software. ![]() In the presence of antioxidants, the enhancement of the electrochemical signal of CYP was registered. A sensitive electrochemical CYP-sensor system was proposed as a reliable candidate for investigating the influence of medicinal preparations – ethoxidol (2-ethyl-6-methyl-3-hydroxypyridine malate), mexidol (2-ethyl-6-methyl-3-hydroxypyridine succinate), cytochrome c and L-carnitine – on the CYP redox behavior and electrocatalytic activity. The analysis of the CYP catalytic activity was carried out using a variety of electrochemical techniques, such as cyclic voltammetry, square wave voltammetry and amperometry. Autolab Gpes Software Posted on by admin NOVA is supplied a wide range of data handling and data analysis tools that can be used to process measured data points and apply analysis methods, thus reducing the need for third-party applications. ![]() ![]() The electrochemical activity of cytochrome P450 (CYP) 3A4, 2C9 and 2D6 on a screen-printed graphite electrode nanostructured with gold nanoparticles and stabilized with didodecyldimethylammonium bromide was examined. ![]()
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